ATP5F1E

Across TCGA pan-cancer cohorts, ATP5F1E mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ATP5F1E data layer compared with 20 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ATP5F1E mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ATP5F1E expression acts as an unfavorable survival marker, although some lineages such as LSCC and COAD show a favorable association.

LUAD, LSCC, and COAD are the cancer types where ATP5F1E mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.795	1.000	.005	18	view →
LSCC	OS	Median	All	1.000	0.937	.012	14	view →
COAD	DFS	Median	III,IV	1.000	0.898	.043	12	view →
PDAC	OS	Median	All	0.588	0.493	.038	10	view →
HNSC	DFS	Tertile	III,IV	0.921	0.670	.009	4	view →
CCRCC	OS	Tertile	III,IV	0.531	1.000	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ATP5F1E–LUAD (OS)

Open the LUAD breakdown →