ATP5F1BP1

Across TCGA pan-cancer cohorts, ATP5F1BP1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated ATP5F1BP1 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher ATP5F1BP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP5F1BP1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and COAD show a favorable association.

ESCA, PAAD, and THCA are the cancer types where ATP5F1BP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Quartile	All	0.434	0.686	.001	25	view →
PAAD	OS	Tertile	II,III,IV	0.753	0.541	.008	24	view →
THCA	OS	Tertile	IV	0.095	0.966	<.001	18	view →
COAD	DFS	Median	All	0.829	0.743	.007	13	view →
LUAD	DFS	Tertile	All	0.254	0.387	.037	12	view →
KICH	DFS	Tertile	III,IV	0.043	0.897	.045	9	view →
UVM	DFS	Tertile	III,IV	0.197	0.704	.031	9	view →
READ	OS	Tertile	IV	0.371	1.000	.010	9	view →
KIRP	DFS	Median	II,III,IV	0.802	0.373	.032	8	view →
PCPG	DFS	Tertile	All	0.822	0.950	.021	6	view →
UCEC	OS	Quartile	All	0.819	0.887	.024	4	view →
LGG	OS	Quartile	All	0.335	0.488	.018	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

ATP5F1BP1–ESCA (DFS)

Open the ESCA breakdown →