ATP5F1BP1

Across TCGA pan-cancer cohorts, ATP5F1BP1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ATP5F1BP1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ATP5F1BP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP5F1BP1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

COAD, KICH, and LUAD are the cancer types where ATP5F1BP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP5F1BP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.227	<.001	5	view →
KICH	Female	II,III,IV	+0.052	.017	2	view →
LUAD	Female	III,IV	+0.032	.029	1	view →
KIRC	Male	All	−0.012	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ATP5F1BP1–COAD

Open the COAD breakdown →