ATP5F1AP8

Across TCGA pan-cancer cohorts, ATP5F1AP8 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated ATP5F1AP8 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher ATP5F1AP8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ATP5F1AP8 expression acts as an unfavorable survival marker.

LIHC, MESO, and BLCA are the cancer types where ATP5F1AP8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.393	0.792	<.001	54	view →
MESO	DFS	Tertile	II,III,IV	0.039	0.407	<.001	36	view →
BLCA	OS	Tertile	All	0.480	0.732	<.001	33	view →
CHOL	OS	Tertile	All	0.248	0.738	.008	27	view →
KIRP	DFS	Tertile	II,III,IV	0.138	0.703	<.001	27	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	21	view →
UVM	DFS	Tertile	III,IV	0.071	0.636	<.001	18	view →
PAAD	DFS	Tertile	All	0.207	0.487	.019	18	view →
KICH	DFS	Tertile	III,IV	0.043	0.897	.045	18	view →
STAD	DFS	Quartile	III,IV	0.480	0.638	.018	14	view →
SARC	DFS	Tertile	All	0.227	0.600	.011	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

ATP5F1AP8–LIHC (OS)

Open the LIHC breakdown →