ATP5F1AP10

Across TCGA pan-cancer cohorts, ATP5F1AP10 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated ATP5F1AP10 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ATP5F1AP10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ATP5F1AP10 expression acts as an unfavorable survival marker, although some lineages such as OV and BLCA show a favorable association.

HNSC, LIHC, and OV are the cancer types where ATP5F1AP10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.570	0.699	<.001	125	view →
LIHC	DFS	Tertile	II,III,IV	0.196	0.439	<.001	63	view →
OV	OS	Median	IV	0.809	0.523	.004	52	view →
LUAD	DFS	Tertile	III,IV	0.271	0.662	<.001	48	view →
READ	OS	Tertile	III,IV	0.111	0.890	<.001	27	view →
KIRP	OS	Tertile	III,IV	0.111	0.697	<.001	27	view →
LUSC	OS	Median	All	0.326	0.446	.006	23	view →
THYM	OS	Tertile	II,III,IV	0.549	0.960	.011	18	view →
COAD	OS	Tertile	II,III,IV	0.541	0.802	.014	18	view →
STAD	OS	Tertile	IV	0.126	0.615	.002	18	view →
UCEC	DFS	Tertile	All	0.640	0.842	.006	18	view →
LGG	DFS	Tertile	All	0.712	0.842	.004	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

ATP5F1AP10–HNSC (OS)

Open the HNSC breakdown →