ATP5F1AP10

Across TCGA pan-cancer cohorts, ATP5F1AP10 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ATP5F1AP10’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ATP5F1AP10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP5F1AP10 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, LUSC, and LUAD are the cancer types where ATP5F1AP10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP5F1AP10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.036	.003	9	view →
LUSC	All	All	+0.029	.004	3	view →
LUAD	All	All	+0.012	.032	1	view →
THCA	All	II,III,IV	−0.008	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ATP5F1AP10–HNSC

Open the HNSC breakdown →