ATP5F1A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP5F1A protein abundance is significantly associated with the RNA expression of many other genes, with 11,343 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP5F1A-associated genes across cancer lineages are RCN3, RGS4, and SRPX2. Each is linked with ATP5F1A in more than 5 cancer types. Because this analysis shows association rather than direction, both ATP5F1A-to-partner and partner-to-ATP5F1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP5F1A versus RCN3 in OV, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5F1A→partner) and Y-score (partner→ATP5F1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVRCN3 →-1.247-0.435.001<.00136
OVRGS4 →-1.219-0.327.002.00636
COADSRPX2 →-0.845-0.158.001.00635
LSCCSTARD3NL →-0.699-0.245<.001<.00135
LUADDSE →-0.635-0.285<.001<.00135
OVCOL10A1 →-2.058-0.345.001.00335
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,343 associations by consensus.

ATP5F1A vs RCN3 — OV

Per-sample scatter of ATP5F1A vs RCN3 in OV (Pearson r = -0.45).

Explore this scatter interactively →

Exploration