ATP5F1A

Across TCGA cell cohorts, ATP5F1A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,658 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATP5F1A-associated GO terms across cancer lineages are Defense response to bacterium, Positive regulation of inflammatory response, and Mitochondrial ribosome assembly. Each is linked with ATP5F1A in more than 12 cancer types. Because this analysis shows association rather than direction, both ATP5F1A-to-partner and partner-to-ATP5F1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Defense response to bacterium grouped by ATP5F1A-low versus ATP5F1A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5F1A→partner) and Y-score (partner→ATP5F1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Defense response to bacterium →	-0.170	-1.089	<.001	<.001	3	13
URINARY_TRACT	Positive regulation of inflammatory response →	-0.132	-0.887	<.001	.001	3	12
BLOOD_Lymphoma	Mitochondrial ribosome assembly →	+0.094	+0.755	<.001	<.001	3	12
BONE	Wound healing →	-0.109	-0.487	<.001	<.001	3	12
BONE	Negative regulation of cell adhesion →	-0.074	-0.417	.002	<.001	3	12
BREAST	Response to unfolded protein →	-0.083	-0.751	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,658 associations by consensus.

Defense response to bacterium by ATP5F1A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →