Across TCGA cell cohorts, ATP4B RNA expression is significantly associated with the go_rna of many other GO terms, with 720 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ATP4B-associated GO terms across cancer lineages are Negative regulation of cytokine production, Tetrapyrrole catabolic process, and Porphyrin-containing compound catabolic process. Each is linked with ATP4B in more than 3 cancer types. Because this analysis shows association rather than direction, both ATP4B-to-partner and partner-to-ATP4B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP4B→partner) and Y-score (partner→ATP4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Negative regulation of cytokine production →	-0.033	-0.019	.009	.007	3	4
LUNG_SCLC	Tetrapyrrole catabolic process →	-0.236	-0.582	<.001	.006	3	4
LUNG_SCLC	Porphyrin-containing compound catabolic process →	-0.236	-0.582	<.001	.006	3	4
LUNG_SCLC	Regulation of semaphorin-plexin signaling pathway →	+0.692	+0.630	.003	.002	3	4
LUNG_NSCLC_LUSC	Calcium-independent cell-matrix adhesion →	+0.143	+0.018	.006	.003	3	3
PANCREAS	Positive regulation of bone development →	+0.926	+0.006	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 720 associations by consensus.

Exploration

ATP4B survival (RNA) · tumor vs normal (RNA) · all ATP4B data types