Across TCGA cell cohorts, ATP4B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP4B-associated genes across cancer lineages are MCHR2 and KLHL34. Each is linked with ATP4B in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP4B-to-partner and partner-to-ATP4B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP4B→partner) and Y-score (partner→ATP4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MCHR2 →	+0.021	+3.684	<.001	.006	3	1
LARGE_INTESTINE	KLHL34 →	+0.123	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

ATP4B survival (RNA) · tumor vs normal (RNA) · all ATP4B data types