ATP2C2-AS1

Across TCGA pan-cancer cohorts, ATP2C2-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ATP2C2-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ATP2C2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP2C2-AS1 expression acts as an unfavorable survival marker, although some lineages such as CESC and UCEC show a favorable association.

ACC, KIRC, and PRAD are the cancer types where ATP2C2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.337	0.795	<.001	88	view →
KIRC	DFS	Median	All	0.517	0.701	<.001	76	view →
PRAD	DFS	Tertile	All	0.824	0.939	<.001	24	view →
LAML	DFS	Quartile	All	0.481	0.730	.008	22	view →
CESC	OS	Tertile	IV	0.772	0.256	.011	18	view →
LUSC	DFS	Median	All	0.603	0.712	.006	16	view →
UCEC	OS	Median	All	0.955	0.897	.011	16	view →
MESO	DFS	Median	II,III,IV	0.262	0.638	.003	15	view →
THYM	DFS	Tertile	III,IV	0.876	0.418	.012	12	view →
LIHC	DFS	Quartile	III,IV	0.870	0.272	.004	11	view →
SKCM	OS	Median	All	0.390	0.278	.002	9	view →
COAD	DFS	Tertile	IV	0.701	0.275	.002	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

ATP2C2-AS1–ACC (DFS)

Open the ACC breakdown →