ATP2C2-AS1

Across TCGA pan-cancer cohorts, ATP2C2-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ATP2C2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ATP2C2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ATP2C2-AS1 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, HNSC, and LUSC are the cancer types where ATP2C2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP2C2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−0.655	<.001	11	view →
HNSC	All	All	+0.354	<.001	11	view →
LUSC	All	All	−0.241	.001	4	view →
STAD	All	All	+0.491	.010	3	view →
BLCA	All	III,IV	+0.420	.014	3	view →
PAAD	All	All	+0.780	.033	2	view →
CHOL	All	All	+0.513	<.001	2	view →
COAD	All	All	+0.282	.019	2	view →
KIRC	All	All	+0.049	.042	2	view →
LIHC	Male	All	−0.017	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

ATP2C2-AS1–THCA

Open the THCA breakdown →