ATP2C1

Across TCGA cell cohorts, ATP2C1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ATP2C1-associated genes across cancer lineages are MOGAT1, GATA5, and XAGE5. Each is linked with ATP2C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP2C1-to-partner and partner-to-ATP2C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MOGAT1 grouped by ATP2C1-low versus ATP2C1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2C1→partner) and Y-score (partner→ATP2C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MOGAT1 →	+0.038	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	GATA5 →	+0.006	+4.191	.009	.007	3	1
OVARY	XAGE5 →	+0.255	+5.196	<.001	.005	3	1
CNS	H1-8 →	+0.022	+5.357	<.001	.001	3	1
CNS	SMIM9 →	+0.026	+4.754	<.001	.005	3	1
BREAST	SPINK9 →	+0.079	+4.836	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MOGAT1 by ATP2C1 expression — BLOOD_Lymphoma

Explore this box plot interactively →