ATP2B3

Across TCGA cell cohorts, ATP2B3 mutation is significantly associated with the RNA expression of many other genes, with 317 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP2B3-associated genes across cancer lineages are TCP11X2, SERPINA7, and METTL21A. Each is linked with ATP2B3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP2B3-to-partner and partner-to-ATP2B3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCP11X2 grouped by ATP2B3-low versus ATP2B3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2B3→partner) and Y-score (partner→ATP2B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TCP11X2 →	+0.132	+4.060	<.001	.003	3	2
LUNG_NSCLC_LUAD	SERPINA7 →	+0.004	+3.006	<.001	.005	3	2
LUNG_NSCLC_LUAD	METTL21A →	+0.666	+3.279	.006	.005	3	2
LUNG_NSCLC_LUAD	RGR →	+0.008	+2.481	.004	.005	3	2
LARGE_INTESTINE	C12orf65 →	+0.440	+3.082	.004	.007	3	2
LARGE_INTESTINE	KIAA1328 →	+0.554	+3.364	.001	.002	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 317 associations by consensus.

TCP11X2 by ATP2B3 expression — BLOOD_Leukemia

Explore this box plot interactively →