ATP2B1-AS1

Across TCGA pan-cancer cohorts, ATP2B1-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ATP2B1-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ATP2B1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ATP2B1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

UCS, SKCM, and PAAD are the cancer types where ATP2B1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	II,III,IV	0.667	0.133	<.001	96	view →
SKCM	OS	Tertile	All	0.408	0.213	<.001	63	view →
PAAD	OS	Tertile	All	0.554	0.263	.001	61	view →
COAD	DFS	Quartile	All	0.333	0.606	.004	38	view →
UVM	DFS	Quartile	II,III,IV	0.336	0.806	.004	34	view →
THCA	OS	Quartile	II,III,IV	0.943	1.000	.004	23	view →
KIRC	DFS	Quartile	All	0.780	0.491	.003	19	view →
LUSC	OS	Quartile	All	0.878	0.709	.001	19	view →
KIRP	OS	Quartile	All	0.990	0.872	.012	16	view →
ACC	OS	Median	II,III,IV	0.347	0.866	.007	11	view →
UCEC	DFS	Tertile	All	0.569	0.648	.007	8	view →
HNSC	OS	Median	IV	0.406	0.307	.019	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

ATP2B1-AS1–UCS (DFS)

Open the UCS breakdown →