ATP2B1-AS1

Across TCGA pan-cancer cohorts, ATP2B1-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ATP2B1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ATP2B1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ATP2B1-AS1 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and LUAD are the cancer types where ATP2B1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP2B1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.902	<.001	12	view →
THCA	Male	III,IV	−1.512	<.001	11	view →
LUAD	All	III,IV	−0.993	<.001	11	view →
COAD	All	III,IV	−0.406	<.001	11	view →
KICH	All	III,IV	−1.735	<.001	10	view →
UCEC	All	III,IV	−1.190	<.001	6	view →
BRCA	Female	All	−0.807	<.001	6	view →
LUSC	All	All	−0.370	<.001	6	view →
HNSC	All	All	+0.276	.018	6	view →
BLCA	Male	IV	−0.940	.041	3	view →
KIRP	All	All	−0.649	<.001	3	view →
READ	All	All	−0.713	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ATP2B1-AS1–KIRC

Open the KIRC breakdown →