ATP2A3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP2A3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,262 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP2A3-associated genes across cancer lineages are CYTIP, JCHAIN, and P2RY8. Each is linked with ATP2A3 in more than 5 cancer types. Because this analysis shows association rather than direction, both ATP2A3-to-partner and partner-to-ATP2A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP2A3 versus CYTIP in LSCC, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2A3→partner) and Y-score (partner→ATP2A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCYTIP →+1.187+0.794<.001<.00136
COADJCHAIN →+1.797+0.325<.001.00236
LSCCP2RY8 →+1.087+0.821<.001<.00136
HNSCTENT5C →+1.514+0.648<.001<.00136
LSCCIGLV5-45 →+1.902+0.564<.001<.00136
HNSCIGHM →+2.360+0.590<.001.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,262 associations by consensus.

ATP2A3 vs CYTIP — LSCC

Per-sample scatter of ATP2A3 vs CYTIP in LSCC (Pearson r = 0.77).

Explore this scatter interactively →

Exploration