ATP2A3

Across TCGA patient cohorts, ATP2A3 mutation is significantly associated with the RNA expression of many other genes, with 5,819 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP2A3-associated genes across cancer lineages are RNU6-197P, RNA5SP160, and SLCO1B1. Each is linked with ATP2A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP2A3-to-partner and partner-to-ATP2A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-197P grouped by ATP2A3-low versus ATP2A3-high in SARC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2A3→partner) and Y-score (partner→ATP2A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	RNU6-197P →	+0.412	+5.345	<.001	.005	3	3
LUSC	RNA5SP160 →	+0.485	+3.526	.004	.007	3	3
COAD	SLCO1B1 →	+0.291	+2.851	.007	.004	3	3
UCEC	NDUFS4 →	+0.443	+3.087	<.001	<.001	3	3
UCEC	NDUFB6 →	+0.559	+2.362	<.001	<.001	3	3
UCEC	RPL17P50 →	+0.404	+3.343	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,819 associations by consensus.

RNU6-197P by ATP2A3 expression — SARC

Explore this box plot interactively →