ATP2A3

Across TCGA cell cohorts, ATP2A3 mutation is significantly associated with the RNA expression of many other genes, with 484 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP2A3-associated genes across cancer lineages are SPATA19, ADAD1, and SEPTIN3. Each is linked with ATP2A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP2A3-to-partner and partner-to-ATP2A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA19 grouped by ATP2A3-low versus ATP2A3-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2A3→partner) and Y-score (partner→ATP2A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	SPATA19 →	+0.036	+5.000	<.001	.005	3	2
LUNG_NSCLC_LUAD	ADAD1 →	+0.048	+4.371	<.001	.005	3	2
LARGE_INTESTINE	SEPTIN3 →	+1.144	+2.936	<.001	<.001	3	2
LARGE_INTESTINE	HFE →	+0.813	+2.158	.001	.004	3	2
LARGE_INTESTINE	PIMREG →	+0.849	+2.158	<.001	.004	3	2
LARGE_INTESTINE	SCD5 →	+1.292	+2.158	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 484 associations by consensus.

SPATA19 by ATP2A3 expression — KIDNEY

Explore this box plot interactively →