ATP2A2

Across TCGA patient cohorts, ATP2A2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,019 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP2A2-associated proteins across cancer lineages are SCYL2, MAP4K1, and ARHGEF37_S251. Each is linked with ATP2A2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ATP2A2-to-partner and partner-to-ATP2A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP2A2 versus SCYL2 in LSCC, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2A2→partner) and Y-score (partner→ATP2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SCYL2 →	+0.220	+0.536	<.001	<.001	3	5
LSCC	MAP4K1 →	-0.464	-0.542	<.001	<.001	3	4
LUAD	ARHGEF37_S251 →	-0.842	-0.320	<.001	.001	3	4
BRCA	PTPN11 →	+0.251	+0.615	<.001	<.001	3	4
UCEC	ATXN2 →	+0.234	+0.552	<.001	<.001	3	4
LSCC	CLIP1 →	+0.248	+0.375	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,019 associations by consensus.

ATP2A2 vs SCYL2 — LSCC

Explore this scatter interactively →