Across TCGA cell cohorts, ATP2A1 mutation is significantly associated with the RNA expression of many other genes, with 1,389 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP2A1-associated genes across cancer lineages are CA5A, MRGPRD, and GPR171. Each is linked with ATP2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP2A1-to-partner and partner-to-ATP2A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2A1→partner) and Y-score (partner→ATP2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CA5A →	+0.058	+2.980	.005	.007	3	2
BLOOD_Leukemia	MRGPRD →	+0.349	+2.855	.006	.002	3	2
BLOOD_Leukemia	GPR171 →	+1.216	+3.584	<.001	.004	3	2
LARGE_INTESTINE	CBY1 →	+0.716	+2.936	<.001	<.001	3	2
LARGE_INTESTINE	ZBED4 →	+0.644	+3.459	<.001	<.001	3	2
LARGE_INTESTINE	TRIM35 →	+0.580	+3.321	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,389 associations by consensus.

Exploration

ATP2A1 survival (RNA) · tumor vs normal (RNA) · all ATP2A1 data types