ATP2A1-AS1

Across TCGA pan-cancer cohorts, ATP2A1-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ATP2A1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ATP2A1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ATP2A1-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and UCEC show a favorable association.

KIRC, ACC, and MESO are the cancer types where ATP2A1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.748	0.855	<.001	150	view →
ACC	OS	Median	All	0.416	0.765	<.001	135	view →
MESO	OS	Median	All	0.440	0.640	.001	79	view →
OV	OS	Quartile	III,IV	0.423	0.308	.014	52	view →
UCEC	DFS	Quartile	IV	0.867	0.285	.005	36	view →
SARC	DFS	Tertile	All	0.418	0.650	<.001	35	view →
COAD	DFS	Median	All	0.727	0.850	.007	33	view →
LIHC	OS	Quartile	All	0.577	0.778	<.001	30	view →
LAML	DFS	Quartile	All	0.349	0.637	.003	30	view →
CESC	OS	Quartile	All	0.778	0.421	.001	26	view →
SKCM	OS	Tertile	All	0.251	0.530	.005	23	view →
READ	DFS	Tertile	III,IV	0.833	0.380	.004	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ATP2A1-AS1–KIRC (OS)

Open the KIRC breakdown →