ATP2A1-AS1

Across TCGA pan-cancer cohorts, ATP2A1-AS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of ATP2A1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ATP2A1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP2A1-AS1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

COAD, HNSC, and BLCA are the cancer types where ATP2A1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP2A1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+1.347	<.001	11	view →
HNSC	All	All	+0.488	.001	9	view →
BLCA	All	All	+1.348	<.001	8	view →
LUAD	All	III,IV	+1.019	<.001	8	view →
LIHC	All	II,III,IV	+0.981	<.001	8	view →
LUSC	Female	All	+1.405	<.001	7	view →
UCEC	All	III,IV	+1.611	<.001	6	view →
BRCA	All	All	+1.063	<.001	6	view →
CHOL	Male	All	+1.526	<.001	5	view →
STAD	All	All	+0.682	<.001	4	view →
ESCA	All	All	+0.928	.001	2	view →
READ	Female	All	+0.921	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

ATP2A1-AS1–COAD

Open the COAD breakdown →