ATP23

Across TCGA patient cohorts, ATP23 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,820 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP23-associated proteins across cancer lineages are IRF2BP2, PUS7, and NABP2. Each is linked with ATP23 in more than 4 cancer types. Because this analysis shows association rather than direction, both ATP23-to-partner and partner-to-ATP23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP23 versus IRF2BP2 in HNSC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP23→partner) and Y-score (partner→ATP23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IRF2BP2 →	+0.224	+0.436	<.001	<.001	3	5
HNSC	PUS7 →	+0.524	+0.546	<.001	<.001	3	5
HNSC	NABP2 →	+0.428	+0.622	<.001	<.001	3	4
LSCC	NLE1 →	+0.386	+0.572	<.001	<.001	3	4
UCEC	PIK3CG_S974 →	-0.652	-0.648	<.001	<.001	3	4
LSCC	PLCG2 →	-0.521	-0.549	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,820 associations by consensus.

ATP23 vs IRF2BP2 — HNSC

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