ATP23

Across TCGA cell cohorts, ATP23 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,420 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP23-associated GO terms across cancer lineages are Mitochondrial proton-transporting ATP synthase complex assembly, Proton-transporting ATP synthase complex assembly, and Proton-transporting two-sector ATPase complex assembly. Each is linked with ATP23 in more than 15 cancer types. Because this analysis shows association rather than direction, both ATP23-to-partner and partner-to-ATP23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial proton-transporting ATP synthase complex assembly grouped by ATP23-low versus ATP23-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP23→partner) and Y-score (partner→ATP23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Mitochondrial proton-transporting ATP synthase complex assembly →	+0.133	+1.064	.001	.003	3	16
UPPER_AERODIGESTIVE_TRACT	Proton-transporting ATP synthase complex assembly →	+0.133	+1.064	.001	.003	3	16
BREAST	Proton-transporting two-sector ATPase complex assembly →	+0.114	+1.000	.003	.004	3	15
BLOOD_Leukemia	Centrosome cycle →	+0.076	+0.750	<.001	<.001	3	11
OVARY	Microtubule cytoskeleton organization involved in mitosis →	+0.088	+0.798	<.001	.002	3	10
BLOOD_Lymphoma	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.104	+0.819	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,420 associations by consensus.

Mitochondrial proton-transporting ATP synthase complex assembly by ATP23 expression — UPPER_AERODIGESTIVE_TRACT

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