ATP1B4

Across TCGA cell cohorts, ATP1B4 RNA expression is significantly associated with the go_rna of many other GO terms, with 154 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ATP1B4-associated GO terms across cancer lineages are Regulation of vacuole organization, Positive regulation of autophagosome maturation, and Negative regulation of autophagosome assembly. Each is linked with ATP1B4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP1B4-to-partner and partner-to-ATP1B4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of vacuole organization grouped by ATP1B4-low versus ATP1B4-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP1B4→partner) and Y-score (partner→ATP1B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Regulation of vacuole organization →	+0.051	+0.020	.007	.007	3	3
BLOOD_Myeloma	Positive regulation of autophagosome maturation →	+0.084	+0.035	<.001	.005	3	2
BLOOD_Myeloma	Negative regulation of autophagosome assembly →	+0.119	+0.035	.002	.005	3	2
BLOOD_Myeloma	Regulation of autophagosome assembly →	+0.060	+0.020	<.001	.007	3	2
BLOOD_Myeloma	Growth involved in heart morphogenesis →	-0.839	-0.020	.006	.007	3	2
BLOOD_Myeloma	DNA replication proofreading →	-0.145	-0.036	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 154 associations by consensus.

Regulation of vacuole organization by ATP1B4 expression — BLOOD_Myeloma

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