ATP1B2

Across TCGA patient cohorts, ATP1B2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,259 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATP1B2-associated genes across cancer lineages are SPARCL1, FHL5, and HRC. Each is linked with ATP1B2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ATP1B2-to-partner and partner-to-ATP1B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP1B2 versus SPARCL1 in COAD, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP1B2→partner) and Y-score (partner→ATP1B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SPARCL1 →	+1.552	+0.942	<.001	.001	3	4
COAD	FHL5 →	+0.872	+0.885	.005	.005	3	3
CCRCC	HRC →	+1.812	+0.884	<.001	.004	3	3
CCRCC	SHE →	+0.965	+0.675	.009	.008	3	3
CCRCC	NPR1 →	+1.354	+0.688	.001	.001	3	3
GBM	PDE2A →	+0.703	+0.441	.004	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,259 associations by consensus.

ATP1B2 vs SPARCL1 — COAD

Explore this scatter interactively →