ATP1B2

Across TCGA patient cohorts, ATP1B2 mutation is significantly associated with the RNA expression of many other genes, with 1,479 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP1B2-associated genes across cancer lineages are RNU6-188P, MIR1183, and RPL39P25. Each is linked with ATP1B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP1B2-to-partner and partner-to-ATP1B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-188P grouped by ATP1B2-low versus ATP1B2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP1B2→partner) and Y-score (partner→ATP1B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-188P →	+0.429	+4.748	<.001	.003	3	2
HNSC	MIR1183 →	+0.526	+4.736	<.001	.007	3	2
HNSC	RPL39P25 →	+0.482	+4.425	<.001	.006	3	2
HNSC	RNU7-125P →	+0.631	+4.748	<.001	.003	3	2
PRAD	RN7SKP60 →	+0.202	+5.993	.002	.002	3	2
COAD	MTCO3P10 →	+0.268	+3.736	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,479 associations by consensus.

RNU6-188P by ATP1B2 expression — HNSC

Explore this box plot interactively →