ATP1B2

Across TCGA cell cohorts, ATP1B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,514 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ATP1B2-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase II promoter, DNA-templated transcription initiation, and Nuclear-transcribed mRNA catabolic process. Each is linked with ATP1B2 in more than 12 cancer types. Because this analysis shows association rather than direction, both ATP1B2-to-partner and partner-to-ATP1B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase II promoter grouped by ATP1B2-low versus ATP1B2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP1B2→partner) and Y-score (partner→ATP1B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.089	+0.277	<.001	.006	3	13
STOMACH	DNA-templated transcription initiation →	+0.091	+0.888	<.001	.002	3	12
STOMACH	Nuclear-transcribed mRNA catabolic process →	+0.067	+0.672	<.001	.004	3	11
BONE	Proton motive force-driven ATP synthesis →	+0.114	+1.745	<.001	.002	3	11
OESOPHAGUS	Proton motive force-driven mitochondrial ATP synthesis →	+0.104	+0.644	<.001	.006	3	11
STOMACH	Positive regulation of transcription initiation by RNA polymerase II →	+0.065	+0.803	<.001	.007	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,514 associations by consensus.

Transcription initiation at RNA polymerase II promoter by ATP1B2 expression — UPPER_AERODIGESTIVE_TRACT

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