ATP1A3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP1A3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,209 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATP1A3-associated genes across cancer lineages are MEFV, AQP9, and FCGR3B. Each is linked with ATP1A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP1A3-to-partner and partner-to-ATP1A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP1A3 versus MEFV in UCEC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP1A3→partner) and Y-score (partner→ATP1A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEFV →+1.225+3.115.001<.00133
UCECAQP9 →+2.115+2.161<.001.00633
UCECFCGR3B →+2.830+2.742.001.00533
UCECCXCL3 →+1.511+1.745.004.00133
UCECCXCL5 →+4.087+2.928<.001.00133
UCECCXCL1 →+3.086+1.537.001.00733
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,209 associations by consensus.

ATP1A3 vs MEFV — UCEC

Per-sample scatter of ATP1A3 vs MEFV in UCEC (Pearson r = 0.64).

Explore this scatter interactively →

Exploration