ATP1A3

Across TCGA cell cohorts, ATP1A3 mutation is significantly associated with the RNA expression of many other genes, with 872 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP1A3-associated genes across cancer lineages are TEX53, GRM6, and FGF23. Each is linked with ATP1A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP1A3-to-partner and partner-to-ATP1A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX53 grouped by ATP1A3-low versus ATP1A3-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP1A3→partner) and Y-score (partner→ATP1A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	TEX53 →	+0.087	+4.280	<.001	.001	3	2
STOMACH	GRM6 →	+0.029	+3.794	<.001	.003	3	1
STOMACH	FGF23 →	+0.062	+3.632	.001	.009	3	1
STOMACH	OR10A5 →	+0.035	+3.794	<.001	.003	3	1
STOMACH	OR2D3 →	+0.016	+3.432	<.001	.008	3	1
STOMACH	IFNL3 →	+0.222	+3.632	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 872 associations by consensus.

TEX53 by ATP1A3 expression — STOMACH

Explore this box plot interactively →