ATP1A2

Across TCGA patient cohorts, ATP1A2 mutation is significantly associated with the RNA expression of many other genes, with 3,812 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP1A2-associated genes across cancer lineages are SNORA80C, MRPS15, and C12orf29. Each is linked with ATP1A2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ATP1A2-to-partner and partner-to-ATP1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA80C grouped by ATP1A2-low versus ATP1A2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP1A2→partner) and Y-score (partner→ATP1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SNORA80C →	+0.266	+2.906	<.001	.002	3	4
UCEC	MRPS15 →	+0.364	+1.399	<.001	<.001	3	4
LUSC	C12orf29 →	+0.329	+2.593	.004	.006	3	4
SKCM	TRAIP →	+0.427	+1.957	.001	.001	3	4
UCEC	RBM19 →	+0.221	+2.375	.001	<.001	3	4
UCEC	HROB →	+0.381	+1.399	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,812 associations by consensus.

SNORA80C by ATP1A2 expression — HNSC

Explore this box plot interactively →