ATP13A1

Across TCGA patient cohorts, ATP13A1 mutation is significantly associated with the RNA expression of many other genes, with 2,505 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP13A1-associated genes across cancer lineages are SAP30-DT, GNLY, and KISS1R. Each is linked with ATP13A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP13A1-to-partner and partner-to-ATP13A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAP30-DT grouped by ATP13A1-low versus ATP13A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP13A1→partner) and Y-score (partner→ATP13A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SAP30-DT →	+0.241	+2.016	.007	.001	3	3
COAD	GNLY →	+1.878	+3.584	<.001	.002	3	3
UCEC	KISS1R →	+0.804	+1.595	<.001	<.001	3	3
COAD	MBD2 →	+0.489	+3.348	.001	.004	3	3
COAD	IER3IP1 →	+0.547	+3.419	.002	.004	3	3
COAD	MRM3 →	+0.663	+3.598	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,505 associations by consensus.

SAP30-DT by ATP13A1 expression — UCEC

Explore this box plot interactively →