ATP12A

Across TCGA cell cohorts, ATP12A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,192 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP12A-associated GO terms across cancer lineages are Cellular response to indole-3-methanol, D-xylulose 5-phosphate metabolic process, and Membrane depolarization. Each is linked with ATP12A in more than 5 cancer types. Because this analysis shows association rather than direction, both ATP12A-to-partner and partner-to-ATP12A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to indole-3-methanol grouped by ATP12A-low versus ATP12A-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP12A→partner) and Y-score (partner→ATP12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Cellular response to indole-3-methanol →	+0.109	+0.068	.006	<.001	3	6
BONE	D-xylulose 5-phosphate metabolic process →	+0.230	+0.223	<.001	.007	3	5
LUNG_SCLC	Membrane depolarization →	-0.051	-0.217	.002	.002	3	5
CNS	Regulation of monoatomic cation transmembrane transport →	-0.041	-0.107	<.001	<.001	3	5
OESOPHAGUS	Potassium ion transport →	-0.059	-0.508	.001	.003	2	6
OVARY	Mitochondrial electron transport, cytochrome c to oxygen →	+0.068	+0.154	.005	.004	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,192 associations by consensus.

Cellular response to indole-3-methanol by ATP12A expression — PANCREAS

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