ATP11B

Across TCGA cell cohorts, ATP11B mutation is significantly associated with the RNA expression of many other genes, with 295 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP11B-associated genes across cancer lineages are FIGLA, GGA1, and DEPDC5. Each is linked with ATP11B in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP11B-to-partner and partner-to-ATP11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FIGLA grouped by ATP11B-low versus ATP11B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP11B→partner) and Y-score (partner→ATP11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FIGLA →	+0.023	+2.678	<.001	.005	3	2
LARGE_INTESTINE	GGA1 →	+0.583	+2.502	.004	.005	3	1
LARGE_INTESTINE	DEPDC5 →	+0.556	+2.502	.002	.005	3	1
LARGE_INTESTINE	CBY1 →	+0.540	+2.588	.003	.004	3	1
LARGE_INTESTINE	RHBDD3 →	+0.799	+2.502	.003	.005	3	1
LARGE_INTESTINE	DCAF11 →	+0.511	+2.502	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 295 associations by consensus.

FIGLA by ATP11B expression — LARGE_INTESTINE

Explore this box plot interactively →