ATP11A

Across TCGA patient cohorts, ATP11A mutation is significantly associated with the RNA expression of many other genes, with 4,761 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP11A-associated genes across cancer lineages are KIF20A, UBE3A, and RITA1. Each is linked with ATP11A in more than 3 cancer types. Because this analysis shows association rather than direction, both ATP11A-to-partner and partner-to-ATP11A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIF20A grouped by ATP11A-low versus ATP11A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP11A→partner) and Y-score (partner→ATP11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF20A →	+0.508	+1.439	.001	<.001	3	4
BLCA	UBE3A →	+0.535	+3.220	.005	.009	3	4
COAD	RITA1 →	+0.403	+3.394	<.001	.004	3	4
UCEC	GLOD4 →	+0.426	+1.760	<.001	<.001	3	4
UCEC	TIPIN →	+0.551	+2.343	<.001	<.001	3	4
UCEC	RANBP1 →	+0.437	+2.131	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,761 associations by consensus.

KIF20A by ATP11A expression — UCEC

Explore this box plot interactively →