ATP11A-AS1

Across TCGA pan-cancer cohorts, ATP11A-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ATP11A-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher ATP11A-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP11A-AS1 expression acts as an unfavorable survival marker, although some lineages such as LAML and LUAD show a favorable association.

KICH, ACC, and LIHC are the cancer types where ATP11A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.533	0.910	<.001	104	view →
ACC	OS	Tertile	III,IV	0.251	0.639	<.001	96	view →
LIHC	DFS	Tertile	All	0.394	0.585	.004	48	view →
LGG	OS	Median	All	0.354	0.512	<.001	44	view →
LUSC	DFS	Tertile	II,III,IV	0.462	0.667	.001	32	view →
LAML	DFS	Tertile	All	0.521	0.233	.008	32	view →
MESO	OS	Tertile	IV	0.221	0.701	.002	30	view →
LUAD	DFS	Median	All	0.769	0.597	<.001	29	view →
OV	OS	Quartile	IV	0.206	0.569	.005	18	view →
PAAD	OS	Tertile	II,III,IV	0.736	0.404	.001	15	view →
HNSC	DFS	Tertile	II,III,IV	0.763	0.663	.030	9	view →
PCPG	OS	Tertile	All	0.847	0.977	.046	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ATP11A-AS1–KICH (DFS)

Open the KICH breakdown →