ATP11A-AS1

Across TCGA pan-cancer cohorts, ATP11A-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ATP11A-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ATP11A-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATP11A-AS1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

KIRC, STAD, and LUAD are the cancer types where ATP11A-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP11A-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.039	<.001	8	view →
STAD	All	All	+0.166	<.001	4	view →
LUAD	Female	II,III,IV	−0.122	.001	4	view →
CHOL	All	All	+0.054	.019	3	view →
LUSC	All	All	−0.078	.001	2	view →
COAD	All	All	+0.064	.026	2	view →
BRCA	All	III,IV	−0.022	.010	2	view →
KICH	All	All	−0.018	.014	1	view →
LIHC	All	II,III,IV	+0.010	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ATP11A-AS1–KIRC

Open the KIRC breakdown →