ATP10B

Across TCGA cell cohorts, ATP10B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,410 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP10B-associated GO terms across cancer lineages are Regulation of tolerance induction dependent upon immune response, Tumor necrosis factor-mediated signaling pathway, and Negative regulation of mast cell degranulation. Each is linked with ATP10B in more than 5 cancer types. Because this analysis shows association rather than direction, both ATP10B-to-partner and partner-to-ATP10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of tolerance induction dependent upon immune response grouped by ATP10B-low versus ATP10B-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP10B→partner) and Y-score (partner→ATP10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of tolerance induction dependent upon immune response →	+1.288	+2.438	<.001	<.001	3	6
STOMACH	Tumor necrosis factor-mediated signaling pathway →	+0.063	+1.518	.003	<.001	3	6
LARGE_INTESTINE	Negative regulation of mast cell degranulation →	+1.467	+2.230	<.001	.001	3	6
STOMACH	Negative regulation of NK T cell activation →	+0.221	+1.532	.001	.009	3	6
STOMACH	tRNA wobble uridine modification →	-0.066	-1.767	.001	<.001	3	6
LUNG_NSCLC_LUAD	Response to molecule of fungal origin →	+0.760	+0.501	.005	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,410 associations by consensus.

Regulation of tolerance induction dependent upon immune response by ATP10B expression — LARGE_INTESTINE

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