ATP10B

Across TCGA cell cohorts, ATP10B mutation is significantly associated with the RNA expression of many other genes, with 411 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP10B-associated genes across cancer lineages are IFIT1B, ARL6, and ITGAD. Each is linked with ATP10B in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP10B-to-partner and partner-to-ATP10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFIT1B grouped by ATP10B-low versus ATP10B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP10B→partner) and Y-score (partner→ATP10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	IFIT1B →	+0.052	+3.361	<.001	.006	3	2
LARGE_INTESTINE	ARL6 →	+0.492	+2.502	.002	.005	3	2
LARGE_INTESTINE	ITGAD →	+0.007	+2.288	.001	.002	3	2
LARGE_INTESTINE	VANGL1 →	+0.734	+2.502	.004	.005	3	2
LARGE_INTESTINE	ZNF624 →	+0.575	+2.502	<.001	.005	3	2
LARGE_INTESTINE	DNAH10 →	+0.672	+3.628	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 411 associations by consensus.

IFIT1B by ATP10B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →