Across TCGA patient cohorts, ATP10A mutation is significantly associated with the total protein of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP10A-associated genes across cancer lineages are Myosin-IIa_pS1943, PI3K-p110-a, and eIF4E. Each is linked with ATP10A in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP10A-to-partner and partner-to-ATP10A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP10A→partner) and Y-score (partner→ATP10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Myosin-IIa_pS1943 →	+0.269	+2.340	.009	.017	3	3
SKCM	PI3K-p110-a →	+0.138	+2.700	.045	.006	3	3
UCEC	eIF4E →	+0.175	+3.100	.001	<.001	3	3
UCEC	PDCD4 →	-0.380	-1.253	.002	.016	3	3
UCEC	Annexin-1 →	+0.580	+2.584	<.001	<.001	3	3
UCEC	Bax →	+0.139	+1.425	.029	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

ATP10A survival (RNA) · tumor vs normal (RNA) · all ATP10A data types