ATOH8

Across TCGA cell cohorts, ATOH8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,645 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ATOH8-associated GO terms across cancer lineages are Regulation of mitotic metaphase/anaphase transition, Positive regulation of T cell differentiation, and Vesicle budding from membrane. Each is linked with ATOH8 in more than 6 cancer types. Because this analysis shows association rather than direction, both ATOH8-to-partner and partner-to-ATOH8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic metaphase/anaphase transition grouped by ATOH8-low versus ATOH8-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATOH8→partner) and Y-score (partner→ATOH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mitotic metaphase/anaphase transition →	+0.103	+2.051	.004	.001	3	7
URINARY_TRACT	Positive regulation of T cell differentiation →	+0.075	+1.780	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Vesicle budding from membrane →	+0.064	+1.577	.001	.008	3	6
URINARY_TRACT	Regulation of lymphocyte differentiation →	+0.057	+1.835	<.001	<.001	3	6
LUNG_NSCLC_LUSC	Glycolytic process →	+0.078	+1.631	.001	.007	3	6
SOFT_TISSUE	Regulation of metaphase/anaphase transition of cell cycle →	+0.099	+2.149	.005	.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,645 associations by consensus.

Regulation of mitotic metaphase/anaphase transition by ATOH8 expression — SOFT_TISSUE

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