ATOH7

Across TCGA pan-cancer cohorts, ATOH7 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ATOH7 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher ATOH7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ATOH7 expression acts as an unfavorable survival marker.

SCLC, UCEC, and ESCA are the cancer types where ATOH7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	All	0.055	0.653	<.001	18	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
ESCA	OS	Median	II,III,IV	0.216	0.702	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ATOH7–SCLC (OS)

Open the SCLC breakdown →