ATN1

Across TCGA pan-cancer cohorts, ATN1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ATN1 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ATN1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ATN1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LSCC, CCRCC, and GBM are the cancer types where ATN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	1.000	0.848	.002	31	view →
CCRCC	OS	Median	II,III,IV	0.228	0.979	.003	26	view →
GBM	DFS	Tertile	All	0.788	0.601	.004	14	view →
PDAC	DFS	Tertile	IV	0.934	0.228	.024	12	view →
LUAD	OS	Quartile	All	0.888	1.000	.038	11	view →
HNSC	OS	Median	IV	0.586	0.828	.008	7	view →
UCEC	OS	Tertile	III,IV	1.000	0.497	.048	4	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ATN1–LSCC (DFS)

Open the LSCC breakdown →