ATN1

Across TCGA pan-cancer cohorts, ATN1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of ATN1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ATN1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATN1 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

HNSC, LIHC, and CHOL are the cancer types where ATN1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATN1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.743	<.001	9	view →
LIHC	Female	II,III,IV	+1.499	<.001	8	view →
CHOL	Female	All	+3.056	<.001	5	view →
THCA	All	II,III,IV	−0.373	.008	5	view →
LUAD	All	All	−0.585	<.001	4	view →
BRCA	Female	All	−0.363	<.001	4	view →
UCEC	All	All	−0.349	.038	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

ATN1–HNSC

Open the HNSC breakdown →