ATN1

Across TCGA patient cohorts, ATN1 mutation is significantly associated with the RNA expression of many other genes, with 3,029 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATN1-associated genes across cancer lineages are MIR4757, GLRXP3, and RNU6-1118P. Each is linked with ATN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ATN1-to-partner and partner-to-ATN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4757 grouped by ATN1-low versus ATN1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATN1→partner) and Y-score (partner→ATN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR4757 →	+0.312	+2.873	<.001	.005	3	4
BRCA	GLRXP3 →	+0.442	+3.587	<.001	.006	3	3
BLCA	RNU6-1118P →	+0.173	+3.870	<.001	.009	3	3
BLCA	CYP4A43P →	+0.349	+3.173	<.001	.007	3	3
CESC	RPL23AP40 →	+0.148	+3.150	<.001	.003	3	2
CESC	RNA5SP73 →	+0.224	+4.252	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,029 associations by consensus.

MIR4757 by ATN1 expression — BLCA

Explore this box plot interactively →