ATN1

Across TCGA cell cohorts, ATN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,958 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATN1-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Epigenetic regulation of gene expression, and Heterochromatin formation. Each is linked with ATN1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ATN1-to-partner and partner-to-ATN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by ATN1-low versus ATN1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATN1→partner) and Y-score (partner→ATN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of gene expression, epigenetic →	+0.094	+1.655	<.001	<.001	3	16
BONE	Epigenetic regulation of gene expression →	+0.090	+1.598	<.001	<.001	3	16
BONE	Heterochromatin formation →	+0.091	+1.530	<.001	<.001	3	15
BONE	Heterochromatin organization →	+0.088	+1.350	<.001	<.001	3	15
STOMACH	Regulation of nucleotide-excision repair →	+0.116	+1.158	.004	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.066	+1.060	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,958 associations by consensus.

Negative regulation of gene expression, epigenetic by ATN1 expression — BONE

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