ATMIN

Across TCGA patient cohorts, ATMIN mutation is significantly associated with the RNA expression of many other genes, with 3,676 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATMIN-associated genes across cancer lineages are NSD2, CPSF7, and PSRC1. Each is linked with ATMIN in more than 2 cancer types. Because this analysis shows association rather than direction, both ATMIN-to-partner and partner-to-ATMIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NSD2 grouped by ATMIN-low versus ATMIN-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATMIN→partner) and Y-score (partner→ATMIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NSD2 →	+0.640	+2.148	<.001	<.001	3	3
UCEC	CPSF7 →	+0.316	+2.238	.005	.006	3	3
UCEC	PSRC1 →	+0.563	+2.016	.004	.005	3	3
CESC	CICP13 →	+0.047	+3.890	<.001	.007	3	2
CESC	AKR1B1P4 →	+0.048	+4.507	<.001	.001	3	2
LIHC	RNU5A-3P →	+0.392	+5.618	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,676 associations by consensus.

NSD2 by ATMIN expression — UCEC

Explore this box plot interactively →