ATMIN

Across TCGA pan-cancer cohorts, ATMIN RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ATMIN’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ATMIN RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATMIN is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

HNSC, THCA, and LUAD are the cancer types where ATMIN tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATMIN RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.373	<.001	10	view →
THCA	All	II,III,IV	−0.461	<.001	9	view →
LUAD	Male	II,III,IV	+0.589	<.001	7	view →
LUSC	Male	All	+0.475	<.001	6	view →
CHOL	Male	All	+1.585	<.001	5	view →
LIHC	All	All	+0.302	<.001	4	view →
BLCA	Male	All	+0.443	.011	3	view →
BRCA	Female	All	−0.136	.016	3	view →
KICH	All	All	−0.351	.027	2	view →
KIRP	Female	II,III,IV	+0.338	.025	2	view →
KIRC	All	All	+0.146	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ATMIN–HNSC

Open the HNSC breakdown →