ATMIN

Across TCGA cell cohorts, ATMIN mutation is significantly associated with the drug of many other genes, with 32 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATMIN-associated genes across cancer lineages are Bosutinib, AZD7762, and GW441756. Each is linked with ATMIN in more than 1 cancer types. Because this analysis shows association rather than direction, both ATMIN-to-partner and partner-to-ATMIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bosutinib grouped by ATMIN-low versus ATMIN-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATMIN→partner) and Y-score (partner→ATMIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Bosutinib →	+0.433	+2.807	.014	.046	3	1
LARGE_INTESTINE	AZD7762 →	+0.606	+2.868	.011	.022	3	1
LARGE_INTESTINE	GW441756 →	+0.570	+2.807	<.001	.046	3	1
LARGE_INTESTINE	KU-55933 →	+0.448	+2.807	.011	.046	3	1
LARGE_INTESTINE	NU7441 →	+0.432	+2.807	.034	.046	3	1
LARGE_INTESTINE	Mirin →	+0.393	+2.868	.028	.022	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Bosutinib by ATMIN expression — LARGE_INTESTINE

Explore this box plot interactively →